Browsing by Subject "Metabolism"
Now showing items 1-2 of 2
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Aging-related diseases and autophagy
(2016)Autophagy is fundamental, evolutionary conserved physiological process at molecular level which targets long-lived cytosolic proteins and organelles to be recycled through lysosomal degradation. Diminished autophagic ... -
Inhibition of autophagy enhances DENSpm-induced apoptosis in human colon cancer cells in a p53 independent manner
(Springer, Van Godewijckstraat 30, 3311 Gz Dordrecht, Netherlands, 2018-06)One of the recently developed polyamine (PA) analogues, N (1) ,N (11)-diethylnorspermine (DENSpm), has been found to act as an apoptotic inducer in melanoma, breast, prostate and colon cancer cells. Also, its potential to ...