Now showing items 1-2 of 2

    • Aging-related diseases and autophagy 

      Arisan, Elif Damla; OBAKAN YERLIKAYA, PINAR; Çoker Gürkan , Ajda; Palavan Unsal, Narcin (2016)
      Autophagy is fundamental, evolutionary conserved physiological process at molecular level which targets long-lived cytosolic proteins and organelles to be recycled through lysosomal degradation. Diminished autophagic ...
    • Inhibition of autophagy enhances DENSpm-induced apoptosis in human colon cancer cells in a p53 independent manner 

      Çoker Gürkan, Ajda; Arısan, Elif Damla; Obakan Yerlikaya, Pınar; İlhan, Halime; Ünsal Palavan, Zeynep Narçın (Springer, Van Godewijckstraat 30, 3311 Gz Dordrecht, Netherlands, 2018-06)
      One of the recently developed polyamine (PA) analogues, N (1) ,N (11)-diethylnorspermine (DENSpm), has been found to act as an apoptotic inducer in melanoma, breast, prostate and colon cancer cells. Also, its potential to ...