Publication:
Sensory Evoked And Event Related Oscillations In Alzheimer's Disease: A Short Review

dc.contributor.authorYener, Görsev G.
dc.contributor.authorBaşar, Erol
dc.contributor.authorIDTR142226tr_TR
dc.contributor.authorIDTR143760tr_TR
dc.date.accessioned2016-05-24T13:15:46Z
dc.date.available2016-05-24T13:15:46Z
dc.date.issued2010
dc.description.abstractDiagnosis and treatment of Alzheimer's disease (AD) depend on clinical evaluation and there is a strong need for an objective tool as a biomarker. Our group has investigated brain oscillatory responses in a small group of AD subjects. We found that the de novo (untreated) AD group differs from both the cholinergically-treated AD group and aged-matched healthy controls in theta and delta responses over left frontal-central areas after cognitive stimulation. On the contrary, the difference observed in AD groups upon a sensory visual stimulation includes response increase over primary or secondary visual sensorial areas compared to controls. These findings imply at least two different neural networks, depending on type of stimulation (i.e. cognitive or sensory). The default mode defined as activity in resting state in AD seems to be affected electrophysiologically. Coherences are also very valuable in observing the group differences, especially when a cognitive stimulus is applied. In healthy controls, higher coherence values are elicited after a cognitive stimulus than after a sensory task. Our findings support the notion of disconnectivity of cortico-cortical connections in AD. The differences in comparison of oscillatory responses upon sensory and cognitive stimulations and their role as a biomarker in AD await further investigation in series with a greater number of subjects.tr_TR
dc.identifier.issn1871-4080
dc.identifier.scopus2-s2.0-78649643120
dc.identifier.scopus2-s2.0-78649643120en
dc.identifier.urihttp://hdl.handle.net/11413/1352
dc.identifier.wos284241800001
dc.identifier.wos284241800001en
dc.language.isoen_UStr_TR
dc.publisherSpringer, Van Godewijckstraat 30, 3311 Gz Dordrecht, Netherlandstr_TR
dc.relationCognitive Neurodynamicstr_TR
dc.subjectOscillationstr_TR
dc.subjectEvent Relatedtr_TR
dc.subjectAlzheimertr_TR
dc.subjectDementiatr_TR
dc.subjectP300tr_TR
dc.subjectMild Cognitive Impairmenttr_TR
dc.subjectTheta-Oscillationstr_TR
dc.subjectCortical Rhythmstr_TR
dc.subjectBipolar Disordertr_TR
dc.subjectBrain Dynamicstr_TR
dc.subjectVisual-Cortextr_TR
dc.subjectPhase Synchronizationtr_TR
dc.subjectEpileptic Patientstr_TR
dc.subjectMemory Tasktr_TR
dc.subjectEEGtr_TR
dc.subjectsalınımlartr_TR
dc.subjectOlaya ilişkintr_TR
dc.subjectAlzheimertr_TR
dc.subjectBunaklıktr_TR
dc.subjectHafif Kognitif Bozukluktr_TR
dc.subjectTeta-Titreşimlertr_TR
dc.subjectBipolar Bozukluktr_TR
dc.subjectBeyin Dinamiğitr_TR
dc.subjectGörsel Kortekstr_TR
dc.subjectEpileptik Hastalartr_TR
dc.subjectBellek Görevtr_TR
dc.titleSensory Evoked And Event Related Oscillations In Alzheimer's Disease: A Short Reviewtr_TR
dc.typeArticletr_TR
dspace.entity.typePublication
local.indexed.atSCOPUS
local.indexed.atWOS
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