Publication:
Effect of Probiotic Supplementation After Laparoscopic Sleeve Gastrectomy on Constipation and Gastrointestinal Quality of Life

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Date
2021
Authors
Yıldız, Nida
Baş, Murat
Coşkun, Halil
Yardımcı, Erkan
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Doç. Dr. Mustafa Hasbahçeci
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Abstract

In this study, we aimed to investigate the early effect of probiotic supplementation after Laparoscopic Sleeve Gastrectomy (LSG) on constipation and gastrointestinal quality of life compared to control group. Methods: This study was a prospective, randomized clinical trial. Participants were recruited to Bariatriklab Obesity and Metabolic Surgery Center for LSG. All patients were divided into 2 groups as probiotic and control by using simple randomization. The probiotic group consumed Bifidobacterium animalis lactis BB-12 strain as a probiotic supplement during 6 weeks after LSG. Gastrointestinal Symptom Rating Scale (GSRS), Constipation Severity Instrument (CSI), Patient Assessment of Constipation Quality of Life Scale (PAC-QOL), Bristol Stool Form Scale (BSFS), Gastrointestinal Quality of Life Index (GIQLI) of the patients were recorded before LSG and at the 2nd, 4th, 6th weeks after LSG. Results: The probiotic group had an average age of 37.00±8.92 years (18 female, 12 male), the control group had an average age of 41.03±11.29 years (23 female, 7 male). CSI (16.50 ± 14.76 vs. 31.37 ± 15.34), PAC-QOL (58.53 ± 12.59 vs 72.30 ± 19.70), GSRS (26.83 ± 9.14 vs. 37.93 ± 16.59) and total score mean were lower compared to the control group, GIQLI total score average (147.50 ± 11.79 vs 136.87 ± 18.98) was found higher (p <0.05) in probiotic group. Conclusion: Probiotic supplementation improved the constipation and gastrointestinal quality of life in the early post-LSG period in the probiotic group compared to the control group.

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Keywords
Bariatric Surgery , Gastrointestinal Quality of Life , Constipation , Sleeve Gastrectomy , Probiotics
Citation
YILDIZ N, BAŞ M, COŞKUN H, YARDIMCI E, BATAR N (2021). Effect of probiotic supplementation after laparoscopic sleeve gastrectomy on constipation and gastrointestinal quality of life. Archives of Clinical and Experimental Medicine, 6(3), 117 - 122. 10.25000/acem.980778