Now showing items 41-50 of 97
Celastrol Modulates Lipid Synthesis via PI3K/Akt/mTOR Signaling Axis to finalize Cell Death Response in Prostate Cancer Cells
FASN is key enzyme during lipid biogenesis is associated with prostate cancer. In this study, we aim to investigate the potential role of celastrol, root extracts of Tripterygium wilfordii on modulation of lipid ...
Roscovitine treatment inhibited cell proliferation and induced apoptosis via modulating activity of Stat3 and Foxo1 under control of Akt in LNCaP prostate cancer cells
Cyclin dependent kinases (CDKs) are known activators of nuclear hormone receptors; such as androgen receptor (AR) via modulating several cell survival signaling routes. However, novel CDK inhibitors might also prevent cell ...
Epibrassinolide Induced Apoptosis via Endoplasmic Reticulum Stress Regardless of p53 Expression in Prostate Cancer Cells
Epibrassinolide (EBR) is a member of brassinosteroids a class of plant polyhydroxysteroids, with well-known growth-promoting roles. EBR induces apoptosis in prostate cancer cells both LNCaP expressing functional androgen ...