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  • Cilt.1 Sayı.2 Eylül 2007 / Volume.1 Number.2 September 2007
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Effective Treatment in Amyotrophic Lateral Sclerosis? Invest in Each Player

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Review / İnceleme (222.6Kb)
Author
Chandawrkar, Akash
Özdinler, P. Hande
Type
Article
Date
2007-09
Language
en_US
Metadata
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Abstract
ALS (Amyotrophic lateral sclerosis) is a complex neurodegenerative disorder that affects corticospinal motor neurons in the cortex, corticobrainstem neurons and the spinal motor neurons in the spinal cord. ALS can develop both due to genetic or sporatic causes. The genetic causes of the disease are largerly unknown, but the cellular interactions between motor neurons and their environment are beginning to elicudate insights into the cellular pathogenesis of the disease. Even though cognition, memory and other brain functions are left intact in patient, the severed motor neuron circuitry leaves them paralyzed. To develop therapeutic approaches in ALS, there is a growing need to understand each and every component of the motor neuron circuitry, and their interaction in detail. In this rewiew, we will introduce cellular components of the complex neurocircuitry and discuss their possible contribution for therapeutic approaches in ALS.
Subject
Amyotrophic Lateral Sclerosis
Neuron
Nöron
URI
http://hdl.handle.net/11413/194
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  • Cilt.1 Sayı.2 Eylül 2007 / Volume.1 Number.2 September 2007 [6]

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İstanbul Kültür University

Hakkında |Politika | Kütüphane | İletişim | Send Feedback | Admin

Istanbul Kültür University, Ataköy Campus E5 Karayolu Üzeri Bakırköy 34158, İstanbul / TURKEY
Copyright © İstanbul Kültür University

Creative Commons Lisansı
IKU Institutional Repository, Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

Designed by  UNIREPOS